How Long Does Ayahuasca Last? (And Why You Might Still Be Hugging a Tree Days Later)
So you’ve heard the whispers in the jungle, or maybe just read a Reddit thread at 2am, and you’re wondering: How long does ayahuasca last? Buckle up, cosmic cowboy, and let’s answer that call from the jungle. Whether you’re prepping for your first ceremony (I wrote a book for that in case you are interested) or just curious about what happens when ayahuasca vine meets mind, this wild ride into the mysteries of the Amazon brew is going to answer that burning question—and probably a few you didn’t know you had.
What Is Ayahuasca Anyway?
Ayahuasca is a powerful psychoactive tea brewed from two primary ingredients: the Banisteriopsis caapi vine and the leaves of the Psychotria viridis shrub. One contains MAO inhibitors; the other contains DMT (the DMT is the psychedelic part). When combined, they open a portal to your subconscious, the spirit world, and occasionally, that embarrassing thing you said in 5th grade.

How Long Does Ayahuasca Last?
Let’s get right to it. The effects of ayahuasca typically last 4 to 8 hours, depending on several factors:
- Your dosage (how many cups did you drink?)
- The strength of the brew (which varies wildly)
- Your metabolism and body weight
- Whether you’re drinking with an experienced shaman or Chad in a garage
- How well you prepared your body during the dieta
- How peaceful and relaxed you arrived
Most people start feeling the effects within 30 to 60 minutes after drinking. Peak intensity usually hits around 1 to 2 hours in, and then you gently (or not-so-gently) float back to baseline over the next few hours. My advice: always drink the second cup.
But here’s the kicker: while the ceremony might last less than a workday, the aftereffects can linger for days. You might still feel emotionally raw, insightful, or just plain weird well into the week. So don’t schedule your DMV appointment the day after. Trust me. You are better off seeing your therapist to help integrate or plan a hike in nature. I recommend clearing your calendar for 1-2 days after the ceremony and keep on that diet for a bonus boost.
How Long Does Ayahuasca Stay in Your System?
Ayahuasca is like that one friend who crashes on your couch after a party and then disappears quietly before breakfast. The active compounds (mainly DMT) are usually metabolized and gone from your system within a few hours, thanks to the work of your liver and enzymes. If you purged right after you drank the magic brew, then it’s going to leave you much sooner.
In most drug tests? It won’t even show up. That’s right, DMT isn’t typically included in standard drug screenings. But to be safe, especially for folks in sensitive careers, check out this detailed breakdown from Psychedelic Science Review.
Do People Change After Ayahuasca?
Short answer: Yes. Long answer: Yesssss. And sometimes dramatically so.

Ayahuasca has a reputation for being a soul plumber — clearing emotional blockages, digging up childhood trauma, and giving you a front-row seat to your neuroses. People often report:
- Letting go of grief, fear, or guilt
- Gaining clarity on life purpose
- Quitting bad habits (smoking, drinking, doom-scrolling)
- A deeper connection to nature or spirit
- Reducing or eliminating depression (the list goes on)
Scientific studies back this up. A 2019 study in Frontiers in Pharmacology found that ayahuasca can lead to long-term improvements in mindfulness, well-being, and emotional regulation. Here’s the study.
But not everyone walks away a shamanic superhero. Some need multiple ceremonies to unpack what the vine reveals. It took me 30 ceremonies to weed out bad habits that I had been carrying for decades. Others find it stirs more questions than answers. And a few? They decide plant medicine ain’t for them. All valid. My advice is, please don’t quit after one sit.
What to Expect After Ayahuasca
The ceremony is over. The Icaros have faded. The bucket has (hopefully) been rinsed. Now what? The real work is about to begin.
Here’s what you might experience post-ayahuasca:
1. Emotional Whirlwind
Tears. Laughter. Staring into the trees like they’re old friends. All normal. Emotional detox is part of the integration process. Get ahold of some music to help you integrate and find a ceremony buddy—someone you resonated with during your weekend—to explore ideas and experiences.
2. The Integration Phase
This is when you take those cosmic downloads and turn them into earthbound wisdom. Journaling, therapy, yoga, or simply sitting with what came up can help. You might even want to work with an integration coach. MAPS has resources to help.
3. Changes in Diet and Lifestyle
Many report suddenly craving clean food, ditching alcohol, or waking up early to greet the sunrise. Your body might reject junk after seeing how good “aligned living” feels. Treat your body like a temple.
4. Spiritual Curiosity
Suddenly interested in meditation, energy healing, or the Akashic Records? Welcome to the club.
5. Feeling Off-Balance (Temporarily)
Not everything is roses and rainbows. Some folks feel ungrounded or anxious afterward. This is why integration is crucial. Give yourself grace and find a psychedic coach to work with—send me an email if you are in a pinch and I’ll help you out.
Do You Always Purge on Ayahuasca?
Ah yes, la purga—it’s easy, it’s fun , and it’s healing. Once you get into purging in ceremony, you will miss it when you get home. It is part of the magic and a true gift from the plant spirits. Not everyone purges through he mouth, some shake, some sweat, some make loud noises—purging comes in several forms and variations.

Purging can be:
- Vomiting
- Diarrhea
- Crying
- Yawning
- Shaking
- Laughing uncontrollably
Do you always purge? No. But it’s common. It is a physical and energetic cleansing. Many report feeling lighter, more transparent, and more emotionally free afterward. It’s not a big deal—most first timers worry about this, but it’s just part of the ayahuasca dance.
Fun(ish) fact: in traditional Amazonian cosmology, vomiting isn’t gross — it’s sacred. You’re expelling spiritual gunk. So next time you’re face-down in a bucket, just remember: you’re doing sacred plumbing. When we drink ayahuasca in the jungle, they don’t even give us a bucket—they point to the jungle and tell us to give what is inside back to mother nature.
A Few Tips If You’re Planning to Drink:
- Do the dieta: Avoid alcohol, red meat, sex, and pungent spices for a few days before and after. See my post for more information on the diet.
- Hydrate: But don’t overdo it. The shaman will guide you.
- Have intentions, not expectations: The vine doesn’t care about your plans. Hold your intentions loosely and gently.
- Respect the medicine: Ayahuasca is powerful. Treat it like your wise but unpredictable grandmother.
Final Thoughts
So, how long does ayahuasca last? In terms of hours: about 4 to 8. But in terms of impact? That’s harder to measure. The insights, emotional shifts, and spiritual nudges can ripple through your life for days, months, even years. Ayahuasca is a guide and will help you navigate your life in a new way; it will point you in the direction most beneficial for your healing and transformation.
It’s not a magic pill, nor is it for everyone. But for those called to it, ayahuasca can be a mirror, a guide, and a cosmic reset button. Ayahuasca saved my life and helped heal deep traumas that I carried from childhood, and removed the addictive layers that shielded my heart. However, it’s not a magic pill; you still need to do the hard work of healing yourself and facing deep shadows inside your soul. It takes courage and a strong will to change.
Whether you purge, cry, see jaguars, or sit in silence, remember: the real journey begins when the ceremony ends.
More Resources
- Erowid Ayahuasca Vault — Trip reports, safety tips, and deep dives.
- ICEERS Ayahuasca Guide — Research, legal info, and harm reduction.
- A Guide to Ayahuasca Integration — For the days (and weeks) after.
Happy travels, brave explorer. And don’t forget your bucket.
P.S. If you want more information on getting prepared for your first ceremony, check out my book Ayahuasca For Beginners: Prepare For Your First Ceremony
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